That's odd it works here (Win10).
sounds like it is not saving to ini file, check permission of the config folder and that it not set to read only.
C:\Users\[user name]\AppData\Roaming\ProcessLasso\config
I just checked. The .ini file was modified today. It is not read-only. In security tab system, administrator, and my account all have modification rights in the top five categories checked. Also I tried putting in the complete path of the programs instead of just the exe filename. It did not modify the file and the box was empty once I "OKd out" of the dialogs. Opened the setting back up right away. It is empty.
My system is a bit weird because it was Open Box. It was a gift from someone on another continent so trying to exchange it was just too much hassle. Stuff like Windows Update, Restore Points etc.. do not work. Windows Installer I often have to run it then restore a system image with a rollback program and do it again etc..
But other than those quirks it does work. The only other time I saw .ini file refuse to update was if they are under one of the Program Files folders. But I took ownership of that and all subfolders and that cleared up that issue. Usually in a case like this you close the program, then reopen it and the settings disappeared. But I am seeing them disappear while the program is still running. Really strange.
Edit: As a work-around could you tell me the format of the ini file setting for excluded programs? I wrote a few programs that work by monitoring the active window while running in the tray. It is likely those will be the only ones I need to exclude. At least until we figure it out.

Edit2: The other bit of information.. I cannot do anything with Task Scheduler on my system. Even when I run CpuBalance manually I get the error about not being able to set a scheduled task to run elevated or whatever. I don't know why that would have any effect on this issue but I thought I'd mention it.